What does IgA and IgG do?

Immunoglobulin A (IgA): It’s found in the linings of the respiratory tract and digestive system, as well as in saliva (spit), tears, and breast milk. Immunoglobulin G (IgG): This is the most common antibody. It’s in blood and other body fluids, and protects against bacterial and viral infections.

What does it mean when IgA is high?

High IgA can indicate chronic inflammation or an infection. Most labs consider values above 400 mg/dL in adults high. The upper limit varies by age and is lower in children and adolescents.

How do you treat high IgA levels?

– High blood pressure medications. Taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can lower your blood pressure and reduce protein loss.
– Omega-3 fatty acids.
– Immunosuppressants.
– Statin therapy.
– Diuretics.

Can high IgA be normal?

High IgA (above normal range) Elevated IgA levels are nonspecific, but can be seen in pulmonary and gastrointestinal inflammatory diseases, some autoimmune conditions, liver disease, and plasma cell disorders.

What does a positive IgA test mean?

Tissue Transglutaminase Antibodies (tTG-IgA) the tTG-IgA test will be positive in about 98% of patients with celiac disease who are on a gluten-containing diet. The test’s sensitivity measures how correctly it identifies those with the disease.

What does IgG and IgA test for?

Your body makes different types of immunoglobulins to fight different types of these substances. An immunoglobulins test usually measures three specific types of immunoglobulins. They are called igG, igM, and IgA. If your levels of igG, igM, or IgA are too low or too high, it may be a sign of a serious health problem.

What is the difference between IgG IgE and IgA?

Antibodies help the body mount an immune system response (‘fight’) against foreign invaders. IgA and IgG reactions are known as delayed response reactions, that include food sensitivities, where IgE responses are immediate and are considered a true food allergy.

What does IgA test for?

An IgA test measures the blood level of immunoglobulin A, one of the most common types of antibodies in the body. Antibodies (also called immunoglobulins) are proteins the immune system makes to recognize and get rid of germs.

What does elevated IgG and IgA mean?

High values Levels of IgA also get higher in some autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (SLE), and in liver diseases, such as cirrhosis and long-term (chronic) hepatitis. IgG. High levels of IgG may mean a long-term (chronic) infection, such as HIV, is present.

What does a low IgA and IgM mean?

People with very low immunoglobulin levels, especially IgA, IgG, and IgM, have a higher chance of developing an infection. A very small number of people cannot make IgA and have a higher chance of developing a potentially life-threatening reaction to a blood transfusion.

Is IgA deficiency serious?

Most people with selective IgA deficiency are healthy, but some patients experience more frequent or severe infections. Patients with selective IgA deficiency have a slightly higher risk of having allergies (abnormal immune system reactions to environmental substances or food) and asthma (swollen airways in the lungs).

What does it mean if your IgM is low?

Low levels of IgM may mean your immune system is not working optimally. Because this antibody helps provide protection against bacteria and viruses, having low IgM levels has been associated with a higher risk of recurring infections [8].